Selected publications

For a full list of the laboratory’s publications, please click here. 

Immune Dysregulation in Obesity

Jiang Z, Tabuchi C, Gayer SG, Bapat SP.

Annual Review of Pathology: Mechanisms of Disease. 2025. Jan;20(1):483-509. doi: 10.1146/annurev-pathmechdis-051222-015350. PMID:39854190 

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Obesity alters pathology and treatment response in inflammatory disease

Bapat SP*, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang LJ, Vogel I, Zhou C, Nguyen VQ, Li Z, Chang C, Zhu WS, Hastie AT, He H, Ren X, Qiu W, Gayer SG, Liu C, Choi EJ, Fassett M, Cohen JN, Sturgill JL, Crotty Alexander LE, Suh JM, Liddle C, Atkins AR, Yu RT, Downes M, Liu S, Nikolajczyk BS, Lee IK, Guttman-Yassky E, Ansel KM, Woodruff PG, Fahy JV, Sheppard D, Gallo RL, Ye CJ, Evans RM, Zheng Y, Marson A.

Nature. 2022 Apr;604(7905):337-342. doi: 10.1038/s41586-022-04536-0. Epub 2022 Mar 30. PubMed PMID: 35355021; PubMed Central PMCID: PMC9165753. *co-corresponding authors              

  • Commented in: Bordon Y. Obesity amplifies TH17-type pathology in atopic diseases. Nat Rev Immunol. 2022 May;22(5):274-275. doi: 10.1038/s41577-022-00721-4. PMID: 35393549.
  • Highlighted in NIH Research Matters online blog: https://www.nih.gov/news-events/nih-research-matters/obesity-alters-response-anti-inflammatory-treatment
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SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood

Ng DL*, Goldgof GM*, Shy BR*, Levine AG*, Balcerek J*, Bapat SP*,…Chiu CY.

Nat Commun. 2020 Sep 17;11(1):4698. doi: 10.1038/s41467-020-18468-8. PMID: 32943630; PMCID: PMC7499171. *co-first authors

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Depletion of fat-resident Treg cells prevents age-associated insulin resistance.

Bapat SP, Myoung Suh J, Fang S, Liu S, Zhang Y, Cheng A, Zhou C, Liang Y, LeBlanc M, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM, Zheng Y.

Nature. 2015 Dec 3;528(7580):137-41. doi: 10.1038/nature16151. Epub 2015 Nov 18. PMID: 26580014; PMCID: PMC4670283s

 

  • Commented in: Maillard I, Saltiel AR. Metabolism: Inflammation keeps old mice healthy. Nature. 2015 Dec 3;528(7580):44-6. doi: 10.1038/nature15648. Epub 2015 Nov 18. PMID: 26580010.
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